The primary treatment of the hepatitis C infection involves the use of antiviral drugs that effectively eliminate the virus from the body. The purpose of treatment is to remove all traces of the hepatitis virus in the body within 12 weeks.
There has been significant progress in hepatitis C treatment as of late with the development of newer, direct-acting antiviral drugs. These new drugs are also sometimes used in conjunction with older medicines. These newer antiviral medications are more effective, work faster, and cause fewer side effects than older treatment methods. Given there is a large variety of option, doctors determine the right medication based on each patient’s individual circumstances such as their virus genotype, whether they have cirrhosis, as well as their treatment history.
Given the ongoing efforts in advancing hep c treatments, recommended treatment plans and medicine options are in also in a state of flux. So, it is essential to consult with your physician about your potential treatment options. It is also important to work closely with your healthcare team to help them assess the effectiveness of your treatment.
Here is an overview of the latest medications used in hep c treatment.
Daclatasvir. Approved for hepatitis C genotype 3, this medication is taken once daily along with Sovaldi (). Potential side effects of daclatasvir include tiredness and headaches. Contact your doctor if you become severely lethargic or notice your heart rate slows down significantly.
and velpatasvir. Available under the brand name Epclusa, this medication is used in the treatment of all hep c genotypes. Just like its counterparts, this antiviral drug may cause fatigue and headaches. Epclusa also shouldn’t be used in conjunction with certain medications; consult with your doctor about potential drug interactions.
Glecaprevir and pibrentasvir. Also known by its brand name Mavyret, this medication is used to treat all hep c genotypes with a daily dose of three capsules. This drug may cause lethargy, headaches, and nausea.
Elbasvir and grazoprevir. Also known as Zepatier, this medication is approved for the treatment of genotypes 1,4, and 6. The medication is taken once daily and is especially recommended for those with liver damage, an advanced kidney disease, HIV, or other serious conditions. Similar to other antivirals, Zepatier may cause fatigue, headaches, and stomach pain.
Ledipasvir and . Known as , this drug was the first hep c medication free of approved for the treatment of genotype 1. Shortly after its approval for genotype 1, the FDA also approved the drug for genotypes 4,5, and 6. The medication may cause side effects such as fatigue and headaches.
Featured Image: Depositphotos/© tashatuvango